Diagnostic and therapeutic methods and their application in amyotrophic lateral sclerosis (ALS)
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United States of America Patent
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Jan 9, 2018
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Dec 4, 2012
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Dec 5, 2011
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Abstract
The present invention provides a method of treating, delaying the onset, delaying progression of, reducing the incidence of or reducing the severity of amyotrophic lateral sclerosis in a subject, the method comprising administering to a subject an agent, which interferes with IgG-A2BG2 expression, IgG-A2BG2 function or IgG-A2BG2 interaction with CD16 in said subject.
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