Compositions, treatment systems and methods for improved cooling of lipid-rich tissue
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United States of America Patent
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Jan 9, 2018
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app pub date -
Jan 30, 2015
filing date -
Jan 31, 2014
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Abstract
Compositions and formulations for use with devices and systems that enable tissue cooling, such as cryotherapy applications, for alteration and reduction of adipose tissue are described. Aspects of the technology are further directed to methods, compositions and devices that provide protection of non-targeted cells (e.g., non-lipid-rich cells) from freeze damage during dermatological and related aesthetic procedures that require sustained exposure to cold temperatures. Further aspects of the technology include systems for enhancing sustained and/or replenishing release of cryoprotectant to a treatment site prior to and during cooling applications.
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