Methods for controlling fucosylation levels in proteins

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United States of America Patent

PATENT NO 9856502
SERIAL NO

14905350

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Abstract

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The present invention relates to a method or process for controlling, inhibiting or reducing protein fucosylation in a eukaryote and/or a eukaryotic protein expression system. Said method comprises carrying out the protein expression and/or post-translational modification in the presence of an elevated total concentration of manganese or manganese ions.

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Patent Owner(s)

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BIOCON LIMITEDBANGALORE 560 100 KARNATAKA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Adhikary, Laxmi Bangalore, IN 13 62
Baskar, Dinesh Bangalore, IN 7 35
Bhatnagar, Ankur Bangalore, IN 4 33
Desan, Saravanan Bangalore, IN 4 33
Melarkode, Ramakrishnan Bangalore, IN 25 124
Montero, Casimiro Jose Enrique Havana, CU 10 55
Nair, Pradip Bangalore, IN 20 79
Pai, Harish Venkatraman Bangalore, IN 3 25
Prabhu, Sunaina Sirsi, IN 2 6
Shukla, Kriti Ahmedabad, IN 2 6
Venkataraman, Rasika Bangalore, IN 2 6

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