Methods and compositions for modulating estrogen receptor mutants

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United States of America Patent

PATENT NO 9855270
SERIAL NO

14645578

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Abstract

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Described herein are methods and compositions for treating an ER-related disease condition characterized by a mutation in the ESR1 gene by administering an estrogen receptor modulator. Also described herein are methods of treating hormone resistant-estrogen receptor (ER) positive breast cancers characterized by a mutation in the ESR1 gene by administering an estrogen receptor modulator.

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Patent Owner(s)

Patent OwnerAddress
F HOFFMANN-LA ROCHE AG124 GRENZACHERSTRASSE BASEL 4070

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chow, Maneval Edna San Diego, US 8 166
Friedman, Lori San Carlos, US 64 364
Hager, Jeffrey J San Diego, US 11 216
Joseph, James D San Diego, US 8 186
Qian, Jing San Diego, US 35 391
Roychowdhury, Debasish F San Diego, US 3 57
Sampath, Deepak San Francisco, US 38 340
Smith, Nicholas D San Diego, US 100 994

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