Methods and pharmaceutical compositions for preventing or reducing metastatic dissemination

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9851358
SERIAL NO

15109942

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present invention relates to methods and pharmaceutical compositions for preventing or reducing metastatic dissemination (i.e. reducing motility of cancer cells). In particular, the present invention relates to a method for preventing or reducing metastatic dissemination (i.e. reducing motility of cancer cells) in a subject suffering from a cancer comprising the steps consisting of i) determining the expression level of at least one biomarker selected from the group consisting of soluble CD95L and EMT promoting factors in a sample obtained from the subject, ii) comparing the expression level determined at step i) with a predetermined reference value and iii) administering the subject with a therapeutically effective amount of C16-ceramide or derivatives such as C16-sphingomyelin and C16-glycosphingolipids when the expression level determined at step i) is higher than the predetermined reference value.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
INSERM (INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)101 RUE DE TOLBIAC PARIS F-75013
UNIVERSITE PAUL SABATIER TOULOUSE III118 ROUTE DE NARBONNE TOULOUSE 31400
UNIVERSITE DE BOURGOGNEESPLANADE ERASME DIJON 21000
UNIVERSITE DES ANTILLES ET DE LA GUYANECAMPUS FOUILLOLE POINTE-À-PITRE 97157
UNIVERSITE DE RENNES I35065 RENNES CEDEX
ECOLE DES HAUTES ETUDES EN SANTE PUBLIQUE (EHESP)15 AVENUE DU PROFESSEUR LÉON-BERNARD CS 74312 RENNES CEDEX 35043
CENTRE HOSPITLIER UNIVERSITAIRE DE TOULOUSE2 RUE VIGUERIE HOTEL-DIEU PONT NEUF TOULOUSE F-31300

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Legembre, Patrick Rennes, FR 10 1
Levade, Thierry Toulouse, FR 9 15
Micheau, Olivier Dijon, FR 1 0
Segui, Bruno Toulouse, FR 9 15

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
7.5 Year Payment $3600.00 $1800.00 $900.00 Jun 26, 2025
11.5 Year Payment $7400.00 $3700.00 $1850.00 Jun 26, 2029
Fee Large entity fee small entity fee micro entity fee
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00