Methods of culturing retinal pigmented epithelium cells, including xeno-free production, RPE enrichment, and cryopreservation
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United States of America Patent
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Dec 26, 2017
Issued Date -
N/A
app pub date -
Jan 31, 2013
filing date -
Feb 1, 2012
priority date (Note) -
In Force
status (Latency Note)
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Abstract
The production of high quality retinal pigmented epithelium (RPE) cells is necessary for research and potential therapeutic uses. Especially desirable are methods for the production of RPE cells using xeno-free culture conditions. Disclosed herein are novel methods for the production of RPE cells from pluripotent cells with high yields, including xeno-free production methods. Also provided are methods of efficiently isolating RPE cells from cultures containing heterogeneous cell types, allowing for substantially pure RPE cell cultures to be established. Additionally, novel methods for the cryopreservation of RPE cells are provided.
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Patent Citation Ranking
- 3 Citation Count
- C12N Class
- 53.39 % this patent is cited more than
- 8 Age
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