Triple reuptake inhibitors and methods of their use
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United States of America Patent
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Dec 26, 2017
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app pub date -
Sep 10, 2015
filing date -
Dec 16, 2008
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Abstract
Provided herein are bicyclic compounds and methods of synthesis thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders. Compounds provided herein inhibit reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine (e.g., from the synaptic cleft) and modulate one or more monoamine transporter. Pharmaceutical formulations containing the compounds are also provided.
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