Methods of stratifying patients for treatment with retinoic acid receptor-alpha agonists

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United States of America Patent

PATENT NO 9845508
SERIAL NO

15172045

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Abstract

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The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.

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Patent Owner(s)

Patent OwnerAddress
SYROS PHARMACEUTICALS INC480 ARSENAL STREET SUITE 130 WATERTOWN MA 02472

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Mei Wei Cambridge, US 4 18
Collins, Cindy Cambridge, US 5 23
Eaton, Matthew Lucas Cambridge, US 9 36
Guenther, Matthew G Boston, US 7 25
Ke, Nan Malden, US 10 23
Lopez, Jeremy Allston, US 6 26
McKeown, Michael R Brookline, US 10 119
Orlando, David A Somerville, US 10 23

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