Inactivated chikungunya viruses (CHIKV) comprising an E1-K211E mutation
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United States of America Patent
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Dec 19, 2017
Grant Date -
May 1, 2014
app pub date -
Jun 18, 2012
filing date -
Jun 17, 2011
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Abstract
A vaccine composition for prophylaxis and treatment of Chikungunya virus infections is disclosed which is capable of conferring immunity against any genotypic variants of the Chikungunya virus. More particularly the invention discloses particular nucleotide sequences and their translated proteins thereof, which may be expressed as Virus Like Particles which for use as a vaccine antigens against Chikungunya virus infections. The compositions disclosed in this invention are also protective against any genotypic variants of the Chikungunya virus which may be propagated by any suitable vector of the disease including Aedis albopictus and Aedis aegypti.
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