Cancer treatment using viruses and camptothecins
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United States of America Patent
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Dec 19, 2017
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app pub date -
Jun 28, 2016
filing date -
Apr 27, 2004
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Abstract
Mammalian subjects having a neoplasm are treated with a virus and a camptothecin compound, for example irinotecan or topotecan. The virus is selected from the group consisting of a Newcastle disease virus, a measles virus, a vesicular stomatitis virus, an influenza virus, a Sindbis virus, a picornavirus, and a myxoma virus. The treatment can also include administration of a monoclonal antibody against epidermal growth factor receptor, for example cetuximab.
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