5′-substituted nucleoside compounds
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United States of America Patent
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Dec 12, 2017
Grant Date -
Nov 10, 2016
app pub date -
Apr 27, 2016
filing date -
May 4, 2015
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Abstract
The present invention relates to novel 5′-substituted nucleoside compounds, pharmaceutical compositions comprising the compounds, and methods of using the compounds to treat cancer, more particularly for the treatment of cancer, in particular glioblastomas, melanoma, sarcomas, gastric cancer, pancreatic cancer, cholangiocarcinoma, bladder cancer, breast cancer, non-small cell lung cancer, leukemias including acute myeloid leukemia, and lymphomas.
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