Macrocyclic compounds as TRK kinase inhibitors

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United States of America Patent

PATENT NO 9840519
SERIAL NO

15350888

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Abstract

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Compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein ring A, ring B, W, m, D, R2, R2a, R3, R3a, and Z are as defined herein, are inhibitors of Trk kinases and are useful in the treatment of pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases.

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Patent Owner(s)

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ARRAY BIOPHARMA INC3200 WALNUT ST BOULDER CO 80301

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Andrews, Steven W Boulder, US 121 3409
Condroski, Kevin Ronald Wallingford, US 33 822
Haas, Julia Boulder, US 83 2074
Jiang, Yutong Boulder, US 86 2396
Kolakowski, Gabrielle R Boulder, US 73 976
Seo, Jeongbeob Baltimore, US 52 1260
Yang, Hong-Woon Superior, US 15 312
Zhao, Qian Louisville, US 243 1622

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