P2X4 receptor antagonist

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9873683
APP PUB NO 20160244434A1
SERIAL NO

14903382

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a compound represented by the following general formula (II), wherein, in the formula, R1a to R6a represent hydrogen atom, an alkyl group having 1 to 8 carbon atoms, and the like, Xa represents C or N, Ya represents N or C(═O), provided that when Xa is C, Ya represents N, and when Xa is N, Ya represents C(═O), the double line consisting of the solid line and the broken line represents a single bond or double bond, Aa represents benzene ring, pyridine ring, and the like, Da represents tetrazole ring, imidazole ring, and the like, Ea represents —(CR9aR10a)p-Ta-, and Ga represents benzene ring, pyridine ring, and the like, which has a P2X4 receptor antagonistic activity.

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Patent Owner(s)

Patent OwnerAddress
KYUSHU UNIVERSITY6-10-1 HAKOZAKI HIGASHI-KU FUKUOKA-SHI FUKUOKA 8128581
NIPPON CHEMIPHAR CO LTDTOKYO 101-0032

International Classification(s)

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  • 2014 Application Filing Year
  • C07D Class
  • 5203 Applications Filed
  • 4627 Patents Issued To-Date
  • 88.93 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201420152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Imai, Toshiyasu Tokyo, JP 26 127
Inoue, Kazuhide Tokyo, JP 37 152
Kobayashi, Kunio Saitama, JP 54 505
Saito, Daisuke Tokyo, JP 170 1119
Sakuma, Shogo Saitama, JP 34 221
Ushioda, Masatoshi Tokyo, JP 17 123

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Patent Citation Ranking

  • 2 Citation Count
  • C07D Class
  • 46.30 % this patent is cited more than
  • 7 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges187319391764691101 - 1011 - 2021 - 3031 - 4041 - 5051 - 600100200300400500600700800900100011001200130014001500160017001800190020002100

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