Optical method for detecting Alzheimer's disease by systemic administration of curcumin
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United States of America Patent
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Dec 12, 2017
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Nov 24, 2011
app pub date -
Sep 18, 2009
filing date -
Sep 18, 2008
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Abstract
The present subject matter relates to a non-invasive optical imaging method for monitoring early pathological events specific to Alzheimer's disease (AD), such as the development, amount and location of amyloid plaques. The ability to monitor such events provides a basis for, among other things, AD diagnosis, prognosis and assessment of potential therapies. In addition, the present subject matter introduces novel methods for treating AD and retinal ailments associated with AD. Aβ-plaque detection in living brains is extremely limited, especially at high resolution; therefore the present invention is based on studies focusing on the eyes as an alternative to brain-derived tissue that can be imaged directly, repetitively and non-invasively.
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