Itraconazole analogues and methods of use thereof

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United States of America Patent

PATENT NO 9839636
SERIAL NO

15481542

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Abstract

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Disclosed herein are analogues of itraconazole that are both angiogenesis and hedgehog signaling pathway inhibitors. The compounds are expected to be useful in the treatment of cancer, particularly cancers that are dependent upon the hedgehog signaling pathway such as basal cell carcinoma and medulloblastoma.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF CONNECTICUT400 FARMINGTON AVENUE FARMINGTON CT 06032

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Banerjee, Upasana Houston, US 2 15
Hadden, Matthew Kyle Ellington, US 4 15

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