Process for detection of alzheimer's disease from a serum sample

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United States of America Patent

PATENT NO 9835621
SERIAL NO

14232863

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed is a method of detecting a concentration of a biomarker in a human subject having or being at risk of developing Alzheimer's disease or Mild Cognitive Impairment (MCI). Also disclosed is a process for detecting a concentration of a biomarker in a human subject having or being at risk of developing Alzheimer's disease or Mild Cognitive Impairment (MCI) comprising (a) detecting a first concentration of lipocalin-PDS/TTR complex in a blood sample or urine sample from the subject, (b) determining a second concentration of PDS/TTR complex in a blood sample or urine sample from an unaffected individual, and (c) comparing the first and second concentrations, wherein a lower first concentration as compared to the second concentration is indicative of the subject having or being at risk of developing Alzheimer's disease.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION144 ASTECC BUILDING LEXINGTON KY 40506-0286

International Classification(s)

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  • 2012 Application Filing Year
  • G01N Class
  • 8064 Applications Filed
  • 6361 Patents Issued To-Date
  • 78.89 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201220132014201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lovell, Mark A Mt Vernon, US 5 134
Lynn, Bert C Nicholasville, US 6 27

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges234338094321455621133525105901 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +02505007501000125015001750200022502500275030003250350037504000

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