Isolation of pulmonary arterial endothelial cells from patients with pulmonary vascular disease and uses thereof

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United States of America Patent

PATENT NO 9835617
SERIAL NO

14426488

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Abstract

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The present disclosure provides methods of obtaining, recovering and culturing pulmonary arterial endothelial cells from an individual patient, subjected to a right heart catheterization in regard to diagnosis of pulmonary hypertension. These isolated pulmonary arterial endothelial cells from an individual patient may be utilized to generate cellular phenotyping profile for the cell population, allowing generation of a personalized pharmacotherapy regime to assist the clinician in treatment and prognosis of the disorder for an individual patient.

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Patent Owner(s)

Patent OwnerAddress
ALLEGHENY-SINGER RESEARCH INSTITUTE320 EAST NORTH AVENUE 10TH FLOOR SOUTH TOWER PITTSBURGH PA 15212

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Benza, Raymond L Pittsburgh, US 4 13
Murali, Srinivas Pittsburgh, US 2 1
Passineau, Michael J Pittsburgh, US 6 15
Pollett, Jonathan B Pittsburgh, US 2 1

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