Populations of hematopoietic progenitors and methods of enriching stem cells therefor
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United States of America Patent
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Dec 5, 2017
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Oct 30, 2014
app pub date -
Nov 21, 2012
filing date -
Nov 21, 2011
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Abstract
There is described herein a method of enriching a population of stem cells for hematopoietic progenitors. The method comprises inducing hematopoietic differentiation in a population of human embryonic stem cells or human induced pluripotent stem cells; sorting the population based on expression of CD43 and at least one of CD34, CD31 and CD144; and selecting a fraction that is at least one of CD34+CD43−, CD31+CD43− and CD144+CD43−. Also provided are populations of hematopoietic progenitors obtained by the methods described herein.
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