Fusion proteins for modulating regulatory and effector T cells

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United States of America Patent

PATENT NO 9834610
SERIAL NO

14764024

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Abstract

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The present invention provides fusion proteins that act on the glucocorticoid-induced TNFR family-related gene (GITR) and OX40 signaling pathway. In certain aspects, the proteins of the invention are useful in modulating both regulatory T (Treg) cells and effector T (Teff) cells.

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Patent Owner(s)

Patent OwnerAddress
THOMAS JEFFERSON UNIVERSITY1020 WALNUT STREET PHILADELPHIA PA 19107
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA3600 CIVIC CENTER BOULEVARD 9TH FLOOR PHILADELPHIA PA 19104

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Tykocinski, Mark L Merion Station, US 33 549

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