Antibodies to human programmed death receptor PD-1

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United States of America Patent

PATENT NO 9834605
APP PUB NO 20150232555A1
SERIAL NO

14576448

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Abstract

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Antibodies which block binding of hPD-1 to hPD-L1 or hPD-L2 and their variable region sequences are disclosed. A method of increasing the activity (or reducing downmodulation) of an immune cell through the PD-1 pathway is also disclosed.

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Patent Owner(s)

Patent OwnerAddress
MERCK SHARP & DOHME B V2031 BN HAARLEM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Carven, Gregory John Maynard, US 6 1035
Dulos, Gradus Johannes Elst, NL 7 1035
Van, Eenenneem Hans Nijmegen, NL 3 333

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