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Abstract

A process of stabilizing a bidentate or tridentate phosphorus-based phosphite ester ligand or mixture thereof in a hydrocyanation reaction milieu comprising water, wherein the ligand or ligand mixture comprises one or more of (i) a bidentate biphosphite ligand of formula (III), (R¹²—X¹²) (R¹³—X¹³) P—X¹⁴—Y—X²⁴—P(X²²—R²²) (X²³—R²³) or (ii) a tridentate triphosphite ligand of formula (IIIA) (R¹²—X¹²) (R¹³—X¹³) P—X¹⁴—Y—X³²—P(X³⁴—R³⁴)—(X³³—Y²—R²⁴—P(X²³—R²³)—(X²²—R²²) where each X is oxygen or a bond and each Y is an optionally substituted C6-C20 arylene group, comprising admixing the bidentate and/or tridentate with a stabilizing amount of one or more monodentate phosphite ligand of formula P(X¹—R¹)(X²—R²)(X³—R³) where each X is oxygen or a bond, wherein the monodentate ligand has a rate of hydrolysis greater than the rate of hydrolysis of the bidentate or tridentate ligand in the presence of water in a hydrocyanation reaction milieu, and thereby preserve concentrations and proportions of the bidentate and/or tridentate ligand(s) in the ligand blend.

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First Claim