Systems and methods of compensation for chromatography column volume variations

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United States of America Patent

PATENT NO 9829470
SERIAL NO

14898272

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Abstract

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Provided are systems and methods for adapting to volume variations in microfluidic chromatography columns. A column is calibrated by comparing a parameter of the column with a same parameter of a reference column and generating, by a processor, an adjustment factor in response to the comparison between the parameter of the column with a same parameter of the reference column. Volume differences between the calibrated column and the reference column are compensated for by integrating the generated adjustment factor into a sample separation involving the calibrated column.

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Patent Owner(s)

Patent OwnerAddress
WATERS TECHNOLOGIES CORPORATIONMILFORD MA 01757

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bunner, Bernard Newton, US 34 666
Gerhardt, Geoff C Woonsocket, US 45 441
Gilar, Martin Franklin, US 42 118

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