Chimeric adeno-associated virus/ bocavirus parvovirus vector
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United States of America Patent
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Nov 28, 2017
Grant Date -
Mar 10, 2016
app pub date -
Apr 8, 2014
filing date -
Apr 8, 2013
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Abstract
The invention provides an isolated chimeric virus comprising bocavirus capsid protein, e.g., an isolated chimeric virus comprising human bocavirus capsid protein, and a recombinant adeno-associated viral (AAV) genome, an isolated recombinant bocavirus (rBoV) comprising human bocavirus capsid protein and a recombinant Boy genome, and uses therefor, for example, in gene therapy for diseases in a mammal including diseases with aberrant expression of an endogenous gene product.
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