Compositions comprising an inhibitor of lysine specific demethylase-1

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United States of America Patent

PATENT NO 9828358
SERIAL NO

15344426

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Abstract

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Described herein are amorphous and crystalline forms of pharmaceutically acceptable salts of the lysine specific demethylase-1 inhibitor 4-[2-(4-amino-piperidin-1-yl)-5-(3-fluoro-4-methoxy-phenyl)-1-methyl-6-oxo-1,6-dihydro-pyrimidin-4-yl]-2-fluorobenzonitrile. Also described are pharmaceutical compositions suitable for administration to a mammal that include the lysine specific demethylase-1 inhibitor, and methods of using the lysine specific demethylase-1 inhibitor for treating diseases or conditions that are associated with lysine specific demethylase-1 activity.

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Patent Owner(s)

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CELGENE QUANTICEL RESEARCH INC10300 CAMPUS POINT DRIVE SUITE 100 SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Young K San Marcos, US 71 305
Kaldor, Stephen W San Diego, US 122 1025
Kanouni, Toufike La Jolla, US 103 417
Kreilein, Matthew Michael Hillsborough, US 15 87
Stafford, Jeffrey Alan San Diego, US 99 548
Tavares-Greco, Paula Alessandra Parsippany, US 4 13
Veal, James Marvin Apex, US 109 976

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