Preparation of ioforminol, an x-ray contrast agent
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United States of America Patent
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Nov 28, 2017
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Sep 24, 2015
app pub date -
Sep 17, 2013
filing date -
Sep 27, 2012
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Abstract
The present invention relates to a process for the preparation of Ioforminol, a contrast agent useful in X-ray imaging. More particularly, the invention relates to preparation of Ioforminol from a compound mixture comprising 1-formylamino-3,5-bis(2,3-bis(formyloxy)propan-1-ylcarbamoyl)-2,4,6-trioodobenzene by a process comprising in situ hydrolysis and a bis-alkylation.
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