Method for preparing crystalline insulin

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United States of America Patent

PATENT NO 9822158
SERIAL NO

15038495

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Abstract

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A method for crystallizing insulin or insulin analogs under alkaline conditions and purifying the insulin or insulin analog crystals by filtering through a filter and drying the insulin or insulin analog crystals captured on the filter to produce crystalline insulin or insulin analog crystal compositions is described. In particular aspects, the method may be used to crystalize insulin glargine.

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Patent Owner(s)

Patent OwnerAddress
MERCK SHARP & DOHME LLC126 EAST LINCOLN AVENUE RAHWAY NJ 07065

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ortigosa, Allison D Harrisonburg, US 6 1
Perry, William Longmont, US 18 484
Sierra, Luis Dunellen, US 3 11
Sleevi, Mark C Longmont, US 13 39

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