Removal of high molecular weight aggregates using hydroxyapatite chromatography

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United States of America Patent

PATENT NO 9822143
SERIAL NO

13803071

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Abstract

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This invention relates to the application of hydroxyapatite chromatography to the purification of at least one antibody from a preparation containing high molecular weight aggregates. Further, this invention relates to an integration of ceramic hydroxyapatite chromatography into a combination chromatographic protocol for the removal of high molecular weight aggregates from an antibody preparation.

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Patent Owner(s)

Patent OwnerAddress
WYETH LLCFIVE GIRALDA FARMS MADISON NJ 07940

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gallo, Christopher Windham, US 12 298
Kelley, Brian Medford, US 15 430
Sun, Shujun Brentwood, US 13 402

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