Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors

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United States of America Patent

PATENT NO 9822107
APP PUB NO 20160340351A1
SERIAL NO

15105713

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Abstract

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The invention provides certain thiazole-substituted aminoheteroaryl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein ring R1, R2, R3, R4, ring B, and the subscript r are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).

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MERCK SHARP & DOHME LLC126 EAST LINCOLN AVENUE RAHWAY NJ 07065

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Andresen, Brian M Sharon, US 20 470
Arrington, Kenneth L Lansdale, US 30 748
Butcher, John W Berlin, US 18 428
Ellis, John Michael Needham, US 23 504
Fournier, Jean-Francois Juan les Pins, FR 10 168
Gauthier, Jacques Yves Laval des Rapides, CA 37 898
Northrup, Alan B Reading, US 41 936
Otte, Ryan D Natick, US 34 642
Robichaud, Joel S Dollard-des-Ormeaux, CA 6 136

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