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• 15 United States
• 10 France
• 8 Japan
• 7 China
• 5 Korea
• 2 Other

Patent Owner(s)

Patent Owner	Address
CARL ZEISS MICROSCOPY GMBH	07745 JENA
CARL ZEISS AG	CARL-ZEISS-STRASSE 22 OBERKOCHEN 73447

International Classification(s)

• G02B:OPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
• G01B:MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIME....

Inventor(s)

Inventor Name	Address	# of filed Patents	Total Citations
Thiele, Dirk	Jena, DE	21	1240
# of filed Patents : 21 Total Citations : 1240
Wehe, Carsten	Weimar, DE	6	1
# of filed Patents : 6 Total Citations : 1

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Patent Citation Ranking

• 1 Citation Count
• G02B Class

• 22.62 % this patent is cited more than
• 8 Age

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Maintenance Fees

Fee	Large entity fee	small entity fee	micro entity fee	due date
7.5 Year Payment	$3600.00	$1800.00	$900.00	May 14, 2025
11.5 Year Payment	$7400.00	$3700.00	$1850.00	May 14, 2029

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Surcharge - 7.5 year - Late payment within 6 months	$160.00	$80.00	$40.00
Surcharge - 11.5 year - Late payment within 6 months	$160.00	$80.00	$40.00
Surcharge after expiration - Late payment is unavoidable	$700.00	$350.00	$175.00
Surcharge after expiration - Late payment is unintentional	$1,640.00	$820.00	$410.00

DATE PUBLISHED	PUBLICATION/PATENT NO.	PUBLICATION TYPE
November 14, 2017	US,9817228,B2   US9817228B2	GRANTED PATENT AS SECOND PUBLICATION
May 11, 2017	US,20170131539,A1   US20170131539A1	FIRST PUBLISHED PATENT APPLICATION

Full Text

US Patent No: 9051395

Alpha-1 antitrypsin variant, preparation method thereof and use thereof

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Abstract

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A novel alpha-1 antitrypsin variant, a method of preparing the same, and use thereof are provided. The alpha-1 antitrypsin variant has excellent stability in the body and maintains an inhibitory effect on elastase activities because the blood half-life (t_1/2) and the area under blood drug concentration vs. time curve (AUC) are remarkably increased by adding an N-glycosylation site in animal cells through amino acid mutation between 1^st and 25^th positions of the N-terminus of alpha-1 antitrypsin. Therefore, the alpha-1 antitrypsin variant can be useful in preventing or treating alpha-1 antitrypsin deficiency.

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Description

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Claims

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Legal Events

 

• MAFP2022
• MAFP2018
• I2015
• STCF2015
• P2014
• AS2014
• F2012
• PD2011

Date	Code	Event	Description
Nov 11, 2022	MAFP	MAINTENANCE FEE PAYMENT	free format text: PAYMENT OF MAINTENANCE FEE, 8TH YR, SMALL ENTITY (ORIGINAL EVENT CODE: M2552); ENTITY STATUS OF PATENT OWNER: SMALL ENTITY year of fee payment: 8
Nov 27, 2018	MAFP	MAINTENANCE FEE PAYMENT	free format text: PAYMENT OF MAINTENANCE FEE, 4TH YR, SMALL ENTITY (ORIGINAL EVENT CODE: M2551); ENTITY STATUS OF PATENT OWNER: SMALL ENTITY year of fee payment: 4
Jun 09, 2015	I	Issuance
May 20, 2015	STCF	INFORMATION ON STATUS: PATENT GRANT	free format text: PATENTED CASE
Dec 18, 2014	P	Published
Mar 10, 2014	AS	ASSIGNMENT	free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:PARK, SOON JAE;CHUNG, HYE-SHIN;LEE, SANG MEE;AND OTHERS;REEL/FRAME:032416/0867 Owner name: ALTEOGEN, INC., KOREA, REPUBLIC OF Effective Date: Mar 10, 2014
Aug 13, 2012	F	Filing
Sep 15, 2011	PD	Priority Date