Lu compounds

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United States of America Patent

PATENT NO 9816156
APP PUB NO 20140294700A1
SERIAL NO

14232205

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Abstract

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The present invention relates to a column chromatographic method of manufacturing non-carrier-added high-purity 177Lu compounds for medicinal purposes. In the method in accordance with the invention a cation exchanger and a suitable chelating agent are used. With the method in accordance with the invention it is possible for the first time to provide non-carrier-added high-purity 177Lu compounds in milligram amounts for pharmaceutical-medicinal purposes from 176Yb compounds irradiated with thermal neutrons, the radionuclides 177Lu and 176Yb being present in an approximate mass ratio of 1:102 to 1:1010 for purification.

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Patent Owner(s)

Patent OwnerAddress
ITM ISOTOPE TECHNOLOGIES MUNICH SE85748 GARCHING BEI MÜNCHEN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Harfensteller, Mark Unterschleiβheim, DE 8 72
Marx, Sebastian Freising, DE 4 6
Nikula, Tuomo Ottobrunn, DE 12 57
Zhernosekov, Konstantin München, DE 12 23

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