Method for selection of agents influencing intestinal motility disorders and pain
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Nov 14, 2017
Issued Date -
N/A
app pub date -
Dec 23, 2016
filing date -
Sep 3, 2012
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
A method is provided for evaluating agents for the treatment of different intestinal motility disorders, using distinct methodological parts related to musculature and nerves of the GI tract which communicate with the brain. In particular, the present invention provides a method for the selection of an agent effective for the treatment of an intestinal motility disorder, comprising: a) a step of spatiotemporal (ST) mapping carried out on a gastrointestinal segment to analyze the effect of the agent on gastrointestinal motility; and b) a step of ex vivo nerve bundle recording carried out on a gastrointestinal segment to analyze the effect of the agent on mesenteric afferent nerve firing. Bacterial strains selected by the methods of the invention and the use of the bacterial strains in the treatment of intestinal motility disorders are also provided.
First Claim
Other Claims data not available
Family
International Classification(s)
- 2016 Application Filing Year
- C12R Class
- 232 Applications Filed
- 128 Patents Issued To-Date
- 55.18 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 0 Citation Count
- C12R Class
- 0 % this patent is cited more than
- 8 Age
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | May 14, 2025 |
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | May 14, 2029 |
