Aspartyl-tRNA synthetases

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United States of America Patent

PATENT NO 9816084
APP PUB NO 20140302075A1
SERIAL NO

14360576

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Abstract

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The present invention provides aspartyl-tRNA synthetase derived proteins (DRS polypeptides) with altered cysteine content, compositions comprising the same, and methods of using such polypeptides and compositions for treating or diagnosing a variety of conditions. The DRS polypeptides of the invention have immunomodulatory properties, and exhibit improved activity and stability.

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Patent Owner(s)

Patent OwnerAddress
ATYR PHARMA INC3545 JOHN HOPKINS COURT SUITE #250 SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Adams, Ryan Andrew San Diego, US 19 643
Buechler, Ying Ji Carlsbad, US 4 64
Greve, Jeffrey Berkeley, US 36 416
Mendlein, John D Encinitas, US 118 2854
Piehl, Kristi Helen San Diego, US 18 720
Wu, Chi-Fang San Diego, US 14 168

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