Biodegradable side chain liquid crystal elastomers: smart responsive scaffolds (SRS) for tissue regeneration
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United States of America Patent
Stats
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Nov 14, 2017
Issued Date -
N/A
app pub date -
Apr 14, 2014
filing date -
Apr 15, 2013
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
Controlled biodegradable smart responsive scaffold (SRS) materials enhance attachment and viability of cells, i.e. actively guiding their expansion, proliferation and in some cases differentiation, while increasing their biomechanical functionality is an important key issue for tissue regeneration. Chemically build-in functionality in these biodegradable SRS materials is achieved by varying structural functionalization with biocompatible liquid crystal motifs and general polymer composition allowing for regulation and alteration of tensile strength, surface ordering, bioadhesion and biodegradability, bulk liquid crystal phase behavior, porosity, and cell response to external stimuli. Liquid crystal modification of such polymeric scaffolds is an ideal tool to induce macroscopic ordering events through external stimuli. None of these approaches have been demonstrated in prior art, and the use of biocompatible scaffolds that respond to a variety of external stimuli resulting in a macroscopic ordering event is a novel aspect of the present invention.
First Claim
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International Classification(s)
- 2014 Application Filing Year
- C09K Class
- 2473 Applications Filed
- 1988 Patents Issued To-Date
- 80.39 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 2 Citation Count
- C09K Class
- 24.18 % this patent is cited more than
- 8 Age
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| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | May 14, 2025 |
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