SP-B and SP-C peptides, synthetic lung surfactants, and use thereof
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United States of America Patent
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Nov 14, 2017
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Feb 11, 2013
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Feb 9, 2012
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Abstract
The present invention relates to synthetic lung surfactant compositions that include a novel surface active peptide and a phospholipid, including phospholipase-resistant phospho-glycerol derivatives, phospholipase-resistant phospho-choline derivatives, naturally occurring phospholipids, or a combination thereof. Uses of the surfactant compositions of the present invention to treat endogenous surfactant dysfunctional or deficient lung tissue and to deliver therapeutic agents are also disclosed.
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