Selective glycosidase inhibitors and uses thereof
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United States of America Patent
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Nov 14, 2017
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Dec 11, 2015
filing date -
Dec 23, 2010
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Abstract
The invention provides compounds with enhanced permeability for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc.
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