Targeted therapeutic proteins
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United States of America Patent
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Nov 14, 2017
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app pub date -
Feb 5, 2016
filing date -
Apr 30, 2001
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Abstract
Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
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