Transforming growth factor beta receptor II fusion polypeptides

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United States of America Patent

PATENT NO 9809637
SERIAL NO

15044883

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Abstract

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In certain aspects, the present disclosure relates to polypeptides comprising a truncated, ligand-binding portion of the extracellular domain of TβRII polypeptide useful to selectively antagonize a TβRII ligand. The disclosure further provides compositions and methods for use in treating or preventing TGFβ associated disorders.

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Patent Owner(s)

Patent OwnerAddress
ACCELERON PHARMA INC128 SIDNEY STREET CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Castonguay, Roselyne Malden, US 52 230
Grinberg, Asya Lexington, US 126 552
Kumar, Ravindra Acton, US 261 3174
Sako, Dianne S Medford, US 40 381
Steeves, Rita Stoneham, US 17 379

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