Diagnostic transcript and splice patterns of HPV16 in different cervical lesions

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United States of America Patent

PATENT NO 9803253
APP PUB NO 20120040334A1
SERIAL NO

13128201

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Abstract

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A method is described for differentiating in a subject with HPV16 between (i) a severe form of HPV16 infection and (ii) a mild form of HPV16 infection based on determining the amount of a first gene product and a second gene product in a sample of a subject and calculating a ratio of the amount of the first gene product and the amount of the second gene product. A composition is also described, including an oligonucleotide mixture, and also a kit and a device adapted to carry out the described method.

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Patent Owner(s)

Patent OwnerAddress
DKFZ DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFUNG DES OFFENTLICHEN RECHTSIM NEUENHEIMER FELD 280 HEIDELBERG D-69120

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gissmann, Lutz Wiesloch, DE 25 174
Pawlita, Michael Eschelbronn, DE 11 44
Schmitt, Markus Heidelberg, DE 108 449

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