Indazole-3-carboxamides and their use as Wnt/beta-catenin signaling pathway inhibitors

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United States of America Patent

PATENT NO 9802916
SERIAL NO

14940958

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Abstract

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Indazole-3-carboxamide compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole-3-carboxamide compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

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Patent Owner(s)

Patent OwnerAddress
BIOSPLICE THERAPEUTICS INC9360 TOWNE CENTRE DRIVE SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hood, John San Diego, US 135 5188
Kumar, KC Sunil San Diego, US 30 1875

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