Polymer nanoparticle composite and composition for MRI imaging including same

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United States of America Patent

PATENT NO 9801958
APP PUB NO 20160206759A1
SERIAL NO

14913903

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Abstract

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The present invention provides a safe polymer nanoparticle composite with few side effects, and an MRI contrast agent incorporating said polymer nanoparticle composite. The polymer nanoparticle composite is capable of specifically accumulating on a tumor tissue to selectively extract the tissue, exhibiting high contrast even when used in small amounts, and enabling imaging over prolonged periods of time. This polymer nanoparticle composite is characterized by containing a block copolymer that includes a non-charged hydrophilic polymer chain segment and an anionic polymer chain segment, and MnCaP.

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Patent Owner(s)

Patent OwnerAddress
THE UNIVERSITY OF TOKYOTOKYO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aoki, Ichio Chiba, JP 4 39
Cabral, Horacio Tokyo, JP 11 25
Kataoka, Kazunori Tokyo, JP 143 1776
Kishimura, Akihiro Tokyo, JP 8 49
Kokuryo, Daisuke Chiba, JP 1 1
Mi, Peng Tokyo, JP 4 2
Miura, Yutaka Tokyo, JP 33 501
Nishiyama, Nobuhiro Tokyo, JP 54 425
Saga, Tsuneo Chiba, JP 5 3

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