Use of inhibitors of bruton's tyrosine kinase (Btk)

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United States of America Patent

PATENT NO 9801883
SERIAL NO

15054952

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Abstract

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Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile.

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Patent Owner(s)

Patent OwnerAddress
PHARMACYCLICS INC995 EAST ARQUES AVENUE SUNNYVALE CA 94085

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Buggy, Joseph J Mountain View, US 104 4216
Elias, Laurence Berkeley, US 40 1174
Fyfe, Gwen San Fernando, US 25 1007
Hedrick, Eric Summit, US 24 984
Loury, David J Incline, US 78 4230
Mody, Tarak D Sunnyvale, US 73 3051

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