Pharmaceutical core-shell composite powder and processes for making the same
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
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Oct 31, 2017
Grant Date -
Oct 22, 2015
app pub date -
Nov 8, 2013
filing date -
Nov 12, 2012
priority date (Note) -
In Force
status (Latency Note)
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Abstract
A composite particle including a core with at least one carrier material; a fluidizing material layer on the surface of the core; and an outer layer comprising nanoparticles of an ingestible material distributed in at least one matrix-forming material. A process of making the composite particles includes the steps of dry coating carrier particles with a fluidizing material; preparing a suspension of nanoparticles of an ingestible material distributed in a matrix-forming material; and fluid bed coating the carrier particles with the suspension. The process and products provide quick dissolving composite particles which can be used for delivery of poorly water soluble ingestible materials in suitable dosage forms. The process of the invention reduces or prevents particle agglomeration during fabrication of the composite particles to enable delivery and quick redispersion of nanoparticles of the ingestible material from a dosage form.
First Claim
all claims..Other Claims data not available
Family
Country | kind | publication No. | Filing Date | Type | Sub-Type |
---|---|---|---|---|---|
BR | B1 | BR112015010704 | Nov 08, 2013 | Patent | Grant |
Type : Patent Sub-Type : Grant | |||||
GRANTED PATENT / GRANTED PIPELINE PATENT | Partícula compósita, e, processo para preparar uma partícula compósita | May 31, 2022 | |||
CN | B | CN104968332 | Nov 08, 2013 | Patent | Grant |
Type : Patent Sub-Type : Grant | |||||
GRANTED PATENT FOR INVENTION | Medicinal core-shell composite powder and preparation method thereof | Oct 20, 2020 | |||
JP | B2 | JP6460562 | Nov 08, 2013 | Patent | Grant |
Type : Patent Sub-Type : Grant | |||||
PUBLISHED GRANTED PATENT (SECOND LEVEL) | 医薬コアシェル複合粉末、及びそれを作成するための方法 | Jan 30, 2019 | |||
WO | A1 | WO2014074808 | Nov 08, 2013 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
INTERNATIONAL APPLICATION PUBLISHED WITH INTERNATIONAL SEARCH REPORT | PHARMACEUTICAL CORE-SHELL COMPOSITE POWDER AND PROCESSES FOR MAKING THE SAME | May 15, 2014 | |||
EP | B1 | EP2916824 | Nov 08, 2013 | Patent | Grant |
Type : Patent Sub-Type : Grant | |||||
Patent | PHARMACEUTICAL CORE-SHELL COMPOSITE POWDER AND PROCESSES FOR MAKING THE SAME | Jun 19, 2019 | |||
AR | A1 | AR093449 | Nov 12, 2013 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
INDEPENDENT PATENT APPLICATION | POLVO FARMACEUTICO COMPUESTO DE NUCLEO-RECUBRIMIENTO Y PROCEDIMIENTOS PARA PRODUCIRLO | Jun 10, 2015 |
- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
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NEW JERSEY INSTITUTE OF TECHNOLOGY | 323 DR MARTIN LUTHER KING JR BOULEVARD UNIVERSITY HEIGHTS NEWARK NJ 07102 |
International Classification(s)

- 2013 Application Filing Year
- A61K Class
- 12711 Applications Filed
- 11051 Patents Issued To-Date
- 86.95 % Issued To-Date
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
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Azad, Mohammed A | Harrison, US | 1 | 5 |
# of filed Patents : 1 Total Citations : 5 | |||
Bilgili, Ecevit A | Woodbridge, US | 2 | 9 |
# of filed Patents : 2 Total Citations : 9 | |||
Dave, Rajesh | Princeton, US | 13 | 276 |
# of filed Patents : 13 Total Citations : 276 | |||
Knieke, Catharina | Ludwigshafen, DE | 2 | 26 |
# of filed Patents : 2 Total Citations : 26 | |||
To, Daniel | North Wales, US | 9 | 39 |
# of filed Patents : 9 Total Citations : 39 |
Cited Art Landscape
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Patent Citation Ranking
- 1 Citation Count
- A61K Class
- 45.09 % this patent is cited more than
- 8 Age
Forward Cite Landscape
- No Forward Cites to Display

Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
---|---|---|---|---|
7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Apr 30, 2025 |
11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Apr 30, 2029 |
Fee | Large entity fee | small entity fee | micro entity fee |
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Surcharge - 7.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
Full Text

Legal Events
Date | Code | Event | Description |
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Apr 14, 2021 | MAFP | MAINTENANCE FEE PAYMENT | free format text: PAYMENT OF MAINTENANCE FEE, 4TH YEAR, LARGE ENTITY (ORIGINAL EVENT CODE: M1551); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY year of fee payment: 4 |
Oct 31, 2017 | I | Issuance | |
Oct 11, 2017 | STCF | INFORMATION ON STATUS: PATENT GRANT | free format text: PATENTED CASE |
Oct 22, 2015 | P | Published | |
Apr 22, 2015 | AS | ASSIGNMENT | free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:TO, DANIEL;BILGILI, ECEVIT;DAVE, RAJESH;AND OTHERS;SIGNING DATES FROM 20140313 TO 20150322;REEL/FRAME:035469/0144 Owner name: NEW JERSEY INSTITUTE OF TECHNOLOGY, NEW JERSEY |
Nov 08, 2013 | F | Filing | |
Nov 12, 2012 | PD | Priority Date |

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