Polymeric iron chelating agent

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United States of America Patent

PATENT NO 9796605
SERIAL NO

13979230

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Abstract

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Disclosed is a water-insoluble polymeric iron chelating agent having a polymer backbone and an aromatic ring attached to the polymer backbone through an —NH—CH2— bond, wherein the aromatic ring has one or two first functional groups in the form of hydroxyl group and one or two second functional groups located at the ortho position with respect to the first functional group; and wherein the second functional group is —OH, —COOH, or a group represented by formula (I) wherein A represents —CH3, —CH2—CH3, —CH2—C6H5, —CH2—C5H4N or —CH2—COOH and B represents —CH2—COOH. The water-insoluble polymeric iron chelating agent of the present invention offers the advantages of being capable of selectively chelating iron ions, particularly biologically unstable iron, and being insoluble in water, and moreover not being incorporated in metabolic processes in vivo.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL UNIVERSITY CORPORATION ASAHIKAWA MEDICAL UNIVERSITYASAHIKAWA-SHI HOKKAIDO 078-8510
DISEASE ADSORPTION SYSTEM TECHNOLOGIES CO LTDKANAZAWA-SHI ISHIKAWA 920-0226

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ikuta, Katsuya Hokkaido, JP 11 6
Kohgo, Yutaka Hokkaido, JP 7 8
Nishida, Yuzo Ishikawa, JP 4 2
Sasaki, Katsunori Hokkaido, JP 20 37

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