Asthma susceptibility loci located at chromosome 1q31 for use in diagnostic and therapeutic methods

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United States of America Patent

PATENT NO 9790550
SERIAL NO

12992965

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Abstract

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Methods and composition are provided for diagnosing pediatπc onset asthma based on the single nucleotide polymorphism on chromosome 1q31 wherein said single nucleotide polymorphism is set forth in Table 2 or Table 6 of the instant invention Method and composition are also provided for treating and preventing asthma or other inflammatory conditions in a patient in need thereof compπsing administering an effective amount of an at least one inhibitor which reduces the expression of DENND1 B gene product.

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Patent Owner(s)

  • THE CHILDREN'S HOSPITAL OF PHILADELPHIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hakonarson, Hakon Malvern, US 94 344
Sleiman, Patrick M A Philadelphia, US 1 0

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