Microrna compounds and methods for modulating MIR-21 activity
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United States of America Patent
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Oct 17, 2017
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May 19, 2016
app pub date -
Oct 14, 2015
filing date -
Oct 14, 2015
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Abstract
Described herein are compositions and methods for the inhibition of miR-21 activity. The compositions have certain nucleoside modification patterns that yield potent inhibitors of miR-21 activity. The compositions may be used to inhibit miR-21, and also to treat diseases associated with abnormal expression of miR-21, such as fibrosis and cancer.
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