Methods and compositions for segregating target nucleic acid from mixed nucleic acid samples
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United States of America Patent
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Oct 17, 2017
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Jan 7, 2015
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Jun 27, 2011
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Abstract
The invention provides methods, compositions and kits for segregating a target nucleic acid from a mixed nucleic acid sample. The methods, compositions and kits comprise a non-processive endonuclease (e.g., a restriction enzyme) or an antibody that binds the target nucleic acid (e.g., has methylation specificity). The mixed nucleic acid sample can comprise prokaryotic and eukaryotic nucleic acid and/or nucleic acid from more than one prokaryotic or eukaryotic organisms.
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