Anti-CD276 polypeptides, proteins, and chimeric antigen receptors

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United States of America Patent

PATENT NO 9790282
SERIAL NO

14779586

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Abstract

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Polypeptides and proteins that specifically bind to and immunologically recognize CD276 are disclosed. Chimeric antigen receptors (CARs), anti-CD276 binding moieties, nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions relating to the polypeptides and proteins are also disclosed. Methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal are also disclosed.

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Patent Owner(s)

Patent OwnerAddress
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICESOFFICE OF TECHNOLOGY TRANSFER NATIONAL INSTITUTES OF HEALTH 6701 ROCKLEDGE DRIVE SUITE 700 MSC 7788 BETHESDA MD 20892-7788

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dimitrov, Dimiter S Frederick, US 105 456
Mackall, Crystal L Bethesda, US 22 84
Orentas, Rimas J Chevy Chase, US 49 144
Saha, Saurabh Leawood, US 51 217
St, Croix Bradley Frederick, US 6 24
Zhu, Zhongyu Frederick, US 64 134

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