Radiolabeled active targeting pharmaceutical composition and the use thereof

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United States of America Patent

PATENT NO 9789214
SERIAL NO

14490072

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Abstract

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The present invention is related to a radiolabeled active targeting pharmaceutical composition, including: a bioconjugate and a radionuclide, wherein the bioconjugate includes a biomolecule and a metal nanoparticle, wherein the biomolecule has an affinity for receptors on the surface of a cell membrane and is selected from the group consisting of a peptide and a protein. The present invention further provides a method for evaluating a thermal adjuvant therapy for tumors and a kit thereof. The above-mentioned pharmaceutical composition is applied to evaluate a tumor accumulation time, so as to establish the optimal policy for a radiofrequency- or laser-induced thermal adjuvant therapy for tumors.

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Patent Owner(s)

Patent OwnerAddress
INSTITUTE OF NUCLEAR ENERGY RESEARCH ATOMIC ENERGY COUNCIL EXECUTIVE YUAN R O CNO 1000 WENHUA RD JIAAN VILLAGE LONGTAN DISTRICT TAOYUAN CITY 32546

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Chao-Cheng Taoyuan County, TW 242 2858
Chi, Kwan-Hwa Taoyuan County, TW 12 16
Hsia, Chien-Chung Taoyuan County, TW 5 4
Kao, Hao-Wen Taoyuan County, TW 14 7
Lin, Kun-Liang Taoyuan County, TW 10 4
Lin, Wuu-Jyh Taoyuan County, TW 51 248
Tien, Der-Chi Taoyuan County, TW 4 13
Wang, Hsin-Ell Taoyuan County, TW 9 11
Weng, Mao-Chi Taoyuan County, TW 6 4

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