Methods and compositions for modulating the immune system with arginase I
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United States of America Patent
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Oct 17, 2017
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Apr 28, 2015
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Apr 29, 2014
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Abstract
Methods and compositions comprising recombinant Arginase I proteins which are capable of depleting the plasma arginine levels in a subject are disclosed. The methods and compositions can be used to modulate the activity of the immune system in a subject. Modulation of the immune system is useful in the treatment of immune disorders and in preventing rejection of a transplanted organ, tissue, or cell. The methods and compositions can also be used to treat a bone condition of a subject.
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