Multiplexed KRAS mutation detection assay

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United States of America Patent

PATENT NO 9783856
SERIAL NO

14811266

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Abstract

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Provided herein is reagent mixture comprising multiplexed amplification reagents and flap assay reagents for detecting, in a single reaction, mutant copies of the KRAS gene that contain any of the 34A, 34C, 34T, 35A, 35C, 35T or 38A point mutations. Methods that employ the reagent mix and kits for performing the same are also provided.

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Patent Owner(s)

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EXACT SCIENCES CORPORATION441 CHARMANY DRIVE MADISON WI 53719

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Allawi, Hatim Madison, US 64 1058
Domanico, Michael J Middleton, US 72 912
Lidgard, Graham P Madison, US 142 1165
Oldham-Haltom, Rebecca Marshall, US 18 244
Zou, Hongzhi Middleton, US 70 747

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